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Normalcranialevolution352midsagittalaxisofthereferenceframe Thecoronalsuturelengthwasdeterminedusing11landmarksfromtheleftpteriontotherightpterionThelateralorbitaldistance(LOD)wasdefinedasthedistancebetweentheleftandrightlateralorbitalwallsIBMSPSSStatisticsversion250(IBMCorpArmonkNY,USA)wasusedfordescriptivestatistics Themeanstandarddeviationand95%confidenceintervalswerecalculated fortheseresults TheStudentt-testwasusedtocompareplagiocephalometrymeasurementsonCT-HTandtheCT-ST,aswellasanysexdifferencesbetweentheagegroupsFigure2(A)Exampleofa3Dphotographwithmanuallypositionedlandmarks(red)(B) Themeasurementplanewasusedtodefinetheobliquediameters(green)craniallengthcranialwidthandcircumference(blue)(C)Illustrationofthemeasurementmethodtodeterminethecranialasymmetryscoreandclassification(D)LengthsofthesuturesmeasuredovertheCT-HTsurfaceRESULTSCRANIALINDEX WIDTHLENGTHANDCIRCUMFERENCETheCIwidthlengthandcircumferencemeasurementsovertimeforthe3DphotographsCT-HT,andCT-STaregivenin Table3andFigure3Duringthefirst24monthsofagetheCIfluctuatedbetween75and78forallmodalitiesAfterthisagetheCIincreasedinbothCT-HTandCT-ST.BoththecranialwidthandcraniallengthincreasedovertimeforallmodalitiesCT-HTshowedlowervaluescompared to the othermodalities Allmodalities showed a suddenincreaseinbothcranialwidthandlengthataround18monthsThecircumferencecranialwidthandcranialheightallfollowedthesamepatternofgrowthDifferencesbetweenmalesandfemaleswerecalculatedforallmeasurements(Table3Figures3–5)