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30Chapter2ABSTRACTInsightintothegrowthanddevelopmentofthenormalnewborncranialshapeisessentialtomonitorcranialdevelopmenttodetectanddiagnoseabnormalskullshapesandforthelong-termfollow-upofcraniosynostosissurgeryTheaimofthisstudywastoanalysethegrowthpatternofthecranialshapeofinfantsduringthefirstyearsoflifeusing3Dstereophotogrammetryand3Dcomputedtomography(CT)withadvanced3DevaluationtechniquesAlargesetof3Dphotographs(n=199)andCTscans(n=183)takenbetween ages 0 and 54months was collected Cranial shapes with artefactsandasymmetrieswereremovedTotalvolumesandintracranialvolumeswereobtainedaswellas3Dand2DmeasurementsincludingthecranialwidthcraniallengthcranialindexandsuturelengthsGrowthmapswerecreated forallmodalities toindicate3DgrowthovertimeForthefinalanalysisatotalof1303Dphotographs94hardtissueCTscansand76softtissueCTscanswereused3Dand2Dmeasures volumesgrowthmapsandgrowthanimations wereobtained Anon-uniformgrowthwasrevealedbythe3DgrowthmapsThisstudyaddressestheneedfornormativecranialevolutiondatatomonitorhealthycranialdevelopmentandfordetectionfollow-upandtreatmentplanningincraniosynostosis
