Page 181 - Demo

The eye as a window to the brain1796Figure 2. Optical coherence tomography for assessments of the thickness of retinal nerve fiberlayers. A) Image of the optic disc (left eye). The green circle indicates the peripapillary region used for RNFL thickness measurements and the blue line shows the orientation of the papil relative to the macula. B) Cross section of the peripapillary retina obtained by OCT. The RNFL is the tissue between the red and turquoise line. C) Representation of RNFL thickness (black line) of the different parts of the peripapillary region as assessed with OCT. The green line indicates the reference line, the green area the reference range, the yellow area the borderline range, and the red area the abnormal range. D) Example of an RNFL thickness map. OCT=optical coherence tomography, RNFL=retinal nerve fiber layer, G=global, NS=nasal superior,N=nasal, NI=nasal inferior, TI=temporal inferior, T=temporal, TS=temporal superior.Table 1. Demographic characteristics.22q11.2DS Controls Statistics P aFundoscopy Vessel morphology Mean age, years Male sexN=4929.9 ± 10.924 (49.0%)N=5726.9 ± 8.322 (38.6%)0.110.33Optical coherence tomography RNFL Mean age, years Male sexN=4129.7 ± 10.217 (41.5%)N=4033.0 ± 12.717 (42.5%)0.201.00 Macula Mean age, years Male sexN=1630.8 ± 9.77 (43.8%)N=4032.8 ± 12.916 (40.0%)0.570.80a Independent samples T-tests were used to compare ages and Fisher’s exact tests to compare sex differences between-groups.22q11.2DS=22q11.2 deletion syndrome, RNFL=retinal nerve layer thickness.