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                                    Alveolar iodine tampon packing after impacted third molar surgery improves oral health-related quality of life955to the prescribed ibuprofen 600 mg, the patients in our study also reported the type and dosage of any other over-the-counter (OTC) medications used. Most patients reported the intake of paracetamol 1000 mg in combination with their prescribed medication. This combination is reportedly beneficial for pain relief after third molar surgery.Both study groups reported pain on postoperative day 1. The Monojectsyringe group exhibited a slightly higher pain score on the 1st postoperative day, and the two study groups significantly differed in pain perception on the following days. Additionally, the Monoject syringe group had a higher percentage of patients with intake of prescribed medications on all assessed postoperative days. On the 4th postoperative day, less than 60% of patients in the iodine tampon group were taking prescribed medications, compared with over 80% of the patients in the Monoject syringe group. The two groups also showed differences in other clinical parameters commonly induced as the result of inflammatory responses, such as swelling, trismus, and chewing problems. The differences in these clinical parameters appeared to be higher after the 3rd postoperative day. From these results, it was obvious that the iodine-containing tampon group suffered less postoperative inconvenience. Several factors have been identified as risk factors for the severity of postoperative sequelae [31, 36], including patient’s age, gender, anatomical and surgical variables (e.g., degree of impaction), wound closure techniques, operator experience, and the procedure duration. In the present study, the two groups did not significantly differ in the distribution of men and women, but a t-test for independent observations revealed a significant betweengroup difference in age. However, Pearson’s correlation analysis did not reveal a statistically significant correlation between age and mean OHIP-14 sum scores. This finding is in accordance with results presented by Benediktsdóttiret al. [37]. Moreover, the independent t-test showed no statistically significant correlation between gender and mean OHIP-14 sum scores. All procedures were performed by one specialized oral and maxillofacial surgeon; therefore, operator experience did not influence the results, and could be eliminated as a variable adversely effecting OHRQoL [7, 38-40]. The mean operating duration was significantly lower for the control group (11.07 min) compared to the intervention group (12.18 min), but the difference was clinically irrelevant. 
                                
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