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Alveolar iodine tampon packing after impacted third molar surgery improves oral health-related quality of life895OHIP-14: iodine tampon versus Monoject® syringeTo determine whether the mean OHIP-14 sum score changed during the first postoperative week in the iodine tampon group and the Monoject® syringe group, we carried out two separate repeated measures ANOVA (RMA) comparing the means on each postoperative day (Table 3). The results showed a significant effect of time in the iodine tampon group [F (6, 258) = 61.58, p< 0.001, ηp2 = 0.59], as well as in the Monoject® syringe group [F (6, 252) = 108.99, p < 0.001, ηp2 = 0.72]. For each group, pairwise comparison of the mean OHIP-14 sum scores from the seven postoperative days showed that all measurements declined over time and significantly differed from each other (p< 0.001). We next assessed the extent to which the mean OHIP-14 sum scores differed between the two interventions across the multiple measurements, by performing a repeated measures ANOVA between-subjects factor. The results indicated that there was a statistically significant interaction effect between the factor of time and each intervention (iodine tampon and Monoject® syringe) [F(df = 6, 510) = 3.27, p = 0.004, ηp2 = 0.037]. This meant that the changes in the mean OHIP-14 score over time differed between the two conditions (Figure 1).To investigate the source of the significant interaction effect between the two groups, first, we calculated a mean difference score (i.e., change over time) between the first and second postoperative day, between the second and third postoperative day, etc. Next, we compared the two patient groups with regards to the mean changes for each calculated difference score. Table 4 presents the comparison of differences between the mean OHIP-14 sum scores for the two conditions. The independent-samples t-tests revealed that the difference ∆7-6 was statistically significant (p = 0.048). The independent-samples t-test enabled examination of whether the conditions differed in the mean OHIP-14 sum scores for the 7 post-operative days (Table 3). We found that the mean OHIP-14 sum scores were significantly lower in the iodine tampon group than in the Monoject® syringe group, except on postoperative days 6 and 7.