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Animal experiment: Histological analysis of the LPM reattachment2238ResultsEnthesis integrationIn all samples, storiform collagen was found within the non-translucent implant scaffold. Overall little to no osteogenic activity was found inside the scaffold of the unique section plane per condylar scaffold, apart from a number of isolated bony islands being formed in two samples. (Figs. 3a, b) In both samples bony islands were antero-posteriorly dispersed throughout the scaffold. Both osteocytes and active remodellation were observed in these bony islands. This was indicative of vital tissue activity. Many iron-loaded macrophages were observed in several samples, suggesting the resorption of the bone chips that were inserted during surgery, yet were no longer present.Despite the close approximation of the enthesis to the scaffold in all samples, only two samples were found with bony extension of the enthesis into the implant scaffolding albeit limited.(Fig. 4) No osseous connection was found between the bony enthesis and bony islands in either sample. However, apart from these osseous extensions, all samples were found to have a thin lamellar layer of collagenous tissue between the implant and the bone, ranging from 20 to 150µm, except for one sample where a maximal thickness of 500µm was found. (Fig. 5)Figs. 3a and b: Detailed view of the scaffold interior. Red arro Titanium scaffold Green arro Osteogenic activity inside of scaffold with active remodellation. Orange arro Storiformly organized, dense connective tissuesThe BTJ and adjacent bone of the enthesis were viable in all samples, with a multitude of Haversian canals with osteocytes, osteoblasts and erythrocytes. Active bone remodellation was seen throughout all the Nikolas de Meurechy NW.indd 223 05-06-2024 10:14