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Chapter 8220Fig. 2: ELI23 Ti6Al4V Ramal component of the TMJR. Black arro Ramal component. Green arro subcondylar tunnel with ‘hook-like’ extension. Yellow arro PDS 0 suture. Red arro HadSat coated condyle.The surgery site was then rinsed thoroughly with aqueous chlorohexidine, after which the articular capsule and soft tissues were closed in multiple layers using polyglyconate 910 2-0 (Vicryl; Ethicon J&J, Somerville, NY, USA) for the deeper layers and poliglecaprone 25 2-0 (Monocryl; Ethicon J&J, Somerville NY, USA) for the intra-dermal closure. A 10-ml subdermal deposit of ropivacaine 7.5 mg/ml (Naropin; AstraZeneca, Wilmington DE, USA) was administered for an additive local analgesic effect. Finally, the wound was sprayed with chlorotetracycline hydrochloride (Cyclospray; Dechra Pharmaceuticals PLC, Northwich, United Kingdom) and the incisions were covered with a sterile primary layer and a compressive head bandage for seven days.Post-operative protocol and EuthanasiaAll the sheep were kept in solitary confinement during the first week, while their vital parameters (heart rate, respiratory rate, and body temperature), dietary status (appetite and fluids intake), and excretions were evaluated and recorded daily. Renewal of the compressive bandaging was performed daily, during which the wounds were evaluated for possible signs of infection. Blood samples were also taken daily during the first post-operative week checking the white cell count and formula, as well as the ionogram and inflammatory parameters twice. Post-operative pain Nikolas de Meurechy NW.indd 220 05-06-2024 10:14