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Cranialshapeevaluation633Figure5ThefourprincipalcomponentswhichwereselectedtoidentifythescaphocephalypatientswereusedtomanipulatethemeancranialshapeThisresultedinanelongatedcranialshapewithareducedlateraldiameterColoursindicateavolumeincrease(green)oravolumedecrease(red)SomewhatsurprisingwewereabletofindasignificantdifferencebetweencontrolsandtrigonocephalypatientusingacombinationoffourPCs Thismeansthatalthoughatypicalwedge-shapedforeheadisnotpresentinthedatasetofcontrolsacombinationof fourPCscangeneratea formof trigonocephaly(Figure6)AlsothismodelcanbeusedtosignificantlyidentifytrigonocephalypatientsThePCAmodelusedinthispresentstudyincluded3Dphotographsintheagerangeof3–6monthsAlimitationsisthatthePCAmodelcanonlyrecognizeandanalysethecranialvaultvariationsinthisspecificageinterval Tocompensateforthisandtoincreasetheclinicalusemoreagevariationshouldbeincluded9Onelimitationof3DphotogrammetryisthatonlytheoutersurfaceoftheheadcanbecapturedandnohardtissuestructurescanbeusedforaccuratealignmentofthepatientsSuperimpositionbasedonthecombinationofmanuallyplacedlandmarksontheoutersurfaceandthesemi-automaticCCFPcalculationmaybeasourceofminorvariabilityMoreresearchisneededtoautomatethesuperimpositionof3DphotographsandovercomeinaccuraciesinregistrationAutomaticsuperimpositionwouldalsoreducetheprocessingtimeandimprovereproducibility
