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Cranialshapeevaluation593STATISTICALANALYSISIBMSPSSsoftware(version22001IBMcorpArmonkNY,USA)wasusedtoperformthestatisticaldataanalysisDescriptivestatisticswereusedtoexplorethevariationofthevaluesinthePC’sforthethreedifferentgroups Theabsolutevalues(inSD)ofthefourselectedPCsweresummedforeverycontrolandforeverypatientAStudentpairedttestwasappliedtotestforsignificantdifferencesbetweenthecontrolpopulationandthepatientpopulationbasedonthefourselectedPCs Thelevelofsignificancewassetat5%(p≤005)Figure3ThecumulativeeffectforeveryprincipalcomponentwascalculatedandexpressedasaratioofthetotalvarianceinthecontrolpopulationMostofthevarianceofthecontrolpopulationisdescribedbythefirstprincipalcomponentsRESULTSVARIATIONSIN THENORMALPOPULATIONPCA of the control groupresultedin amean cranial shape of the controlpopulationandasetofPCsdescribingthevariationsinthecontrolpopulation TheeffectofPC1 is displayed inFigure 2 Thismorphological effect is an increase of the completefrontalregiontotheanteriordirectionincludingananteriordisplacementoftheorbitalregionIntotalthecranialshapebecamemoreelongatedwithoutareductionofthelateraldiameterofthecraniumPC1accountedfor46%ofthe