Page 34 - Bladder Dysfunction in the Context of the Bladder-Brain Connection - Ilse Groenendijk.pdf
P. 34
32 Chapter 2
Table 2. Study characteristics of fMRI studies. Main study details
Task
paradigm
Scan details and analysis
Group MNI
Healthy
Study N volunteers? Age M/F
Concomi- tant tasks
Control task
Main task repetition
Bladder status
-TE Bladder -FoV
Smooth Gaussian
analyses or model TAL
Threshold P value
PELVIC FLOOR MUSCLE CONTRACTION
Groenendijk, 13 I.M. et al (2020)
Healthy volunteers
29.6 13/0
PFMC
None
Tongue movement
Block
12
Empty
- 7T - 2000 - 25
Uncorrected
Kutch, J.J. et al 14
(2015) volunteers
- 14/0
PFMC
None
Right hand contraction
Block
6
Empty
- 3T - 2500 - 34.5 - 220
Krhut, J. et al 23
(2014) volunteers
20-68 0/23
PFMC
None
None
Block
10
Unknown
- 3T - 2000 - 20
Uncorrected
Schrum, A. et al 17
(2011) volunteers
28.9 17/0
PFMC
None
Toe movement
Block
6 fast 6 slow
Empty
- 3T - 2500 - 34.5 - 224
FWE <0.05
Seseke, S. et al 12
(2008) volunteers
32.4 12/0
PFMC
None
Rest
Block
15
Full
Natural 3T - 2000 - 36
Brain voyager QX
FDR
Kuhtz- 30 Buschbeck, J.P.
et al (2007)
Healthy volunteers
26.6 15/15
PFMC
None
Rest
Block
5
Variable within subjects
- 1.5T -
- 50
FWE
Seseke, S. et al 11
(2006) volunteers
30 0/11
PFMC
None
Rest
Block
15
Full
Natural 3T - 2000 - 36
Brain voyager QX
FDR
Di Gangi 10 Herms, A.M.R.
et al (2006)
Stress urinary incontinence
57 0/10
PFMC
Pressure balloon in vagina
Fist clenching
Block
11
Empty
- 3T - 3000 - 30
SPM2
9 mm
- MNI
Corrected <0.05
Healthy
FMRIB
5 mm
Mixed effects MNI
Cluster based cor
<0.05
Healthy
Healthy
Healthy
Healthy
Main task
filling Tesla -ST
Software
Design: Block or event related
-TR
- 223 - 1.75
-3
- 192 -
-3
- -4
- 220 -3
- -4
- -3
SPM8
2.5 mm
Random MNI
effects <0.001
SPM8
6 mm
Random MNI
effects P = 0.0001
SPM5
6 mm
Random MNI
effects corrected
SPM2
7 mm
Random MNI
effects p = variable
8 mm
Random TAL
effects <0.05
4 mm
Random TAL
effects <0.05