Page 36 - Bladder Dysfunction in the Context of the Bladder-Brain Connection - Ilse Groenendijk.pdf

34 Chapter 2
Table 3. Study characteristics of PET studies. Abbreviations: GBq: the amount of gigabecquerel H215O (in case of Blok et al diluted in saline) injected before PET scan. TAL: Talairach.
Main study details
Task paradigm
Scan details and analysis - GBq
Age PELVIC FLOOR MUSCLE CONTRACTION
M/F
Main task
Software
Gaussian model
Study N
Blok B.F.M. et al (1997)
6HV
21 - 24
0/6
PFMC
None
rest
1
Block
empty
-
- -20 - 76
- 1.85 -23 sec - 90 sec -4
-2.2
SPM96
12 ANCOVA
Tal
Uncorrected <0.001
MICTURITION
Nour S. et al (2000)
8a HV
23.4 ± 1.1 (22 – 25)
8/0
Micturition
None
rest
2 -4
Event related
filled to desire
Catheter
- -
- 0.4
- 30 sec - 90 sec - 10 – 12 -
SPM96
10 -
Tal
variable
Blok, B.F.M. et al (1998)
10b HV
27 (20-51)
0/10
Micturition
None
Empty bladder
1
Block
full
Natural
- 28 mm - 48 mm
- 1.85
- 23 sec - 90 sec -4
- 2.2
SPM95
8 ANCOVA
Tal
Uncorrected <0.001
Blok B.F.M. et al (1997)
10c HV
32.3 (21-50)
10/0
Micturition
None
Empty bladder
1
Block
full
Natural
-28 mm -44 mm
- 1.85
- 23 sec - 90 sec -4
- 2.2
SPM95
8 ANCOVA
Tal
Uncorrected P = variable
Healthy volunteers = HV
Concomitant tasks
Control task
Main task repeti-tion
Design: Block or event related
Bladder status
Bladder filling
camera position -below -above
- start scan after injection - data acquisition
- repeat injection
- voxel size
Group Smooth analyses
MNI or TAL
Threshold P value
a 12 patients were included but only 8 performed successful micturition
b 18 patients were included but only 10 performed successful micturition c 17 patients were included but only 10 performed successful micturition