Page 277 - Prevention and Treatment of Incisional Hernia- New Techniques and Materials

Macrophages in a contaminated environment
Figure 5. Comparison of secretion of proin ammatory cytokines by macrophages seeded on di erent biomaterials on the third day of culture with lipopolysaccharide/interferonγ, corrected for DNA. a Tumour necrosis factor (TNF) α, b interleukin (IL)1β, c monocyte chemotactic protein (MCP)3; d IL-6, e macrophage in ammatory protein (MIP) 1α. Monocytes from a total of four donors were divided over the di erent biomaterials in triplicate samples. Cells from all donors could not be tested on every biomaterial owing to a low yield of monocytes. PET+COL, polyethylene terephthalate with a collagen coating; COL, collagen; PET, polyethylene terephthalate; PP, polypropylene. a *P<0•001 (PET+COL versus COL), †P < 0•050 (PET+COL versus PET), ‡P < 0.050 (COL versus PP); b †P < 0•050 (PET+COL versus COL and PET ), ‡P < 0•050 (COL versus PET and PP); c *P < 0•001 (COL versus PET+COL and PET ), †P < 0•050 (COL versus PP); d †P < 0•050 (COL versus PET and PP); e *P < 0•001 (COL versus PET+COL and PP) (Kruskal– Wallis and Mann–Whitney U tests)
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