Page 50 - Pro-active Management of Women’s Health after Cardiometabolic Complicated Pregnancies

48 | Part 2 Cardiovascular Health
Table 2.2.2. Prevalence of thrombophilia factors (figures presented as % (total tested in subgroup), bold and greyed numbers represent p < 0.05)
Factor
≥1 thrombophilia factor Anti-phospholipid antibodies Protein-Cdeficiency Protein-Sdeficiency
APC Resistance (FVL excluded) Hyperhomocysteineamia Factor V Leiden (heterozygous) Prothrombin gene mutation (heterozygous)
≥1 thrombophilia factor Anti-phospholipid antibodies
Protein-C deficiency Protein-S deficiency
APC Resistance (FVL excluded) Hyperhomocysteineamia Factor V Leiden (heterozygous) Prothrombin gene mutation (heterozygous)
≥1 thrombophilia factor Anti-phospholipid antibodies
Protein-C deficiency Protein-S deficiency
APC Resistance (FVL excluded) Hyperhomocysteineamia Factor V Leiden (heterozygous) Prothrombin gene mutation (heterozygous)
Overall
239/740 (32.3%)
59/759 (7.8%) 6/778 (0.8%) 99/720 (13.8%)
45/640 (7.0%) 125/424 (29.5%)
38/807 (4.7%) 25/806 (3.1%)
Preeclampsia severity Mild Severe
HELLP syndrome
Absent Present 108/369 (29.3%) 131/371 (35.3%)
12/68 (17.6%)
227/672 (33.8%)
3/72 (4.2%) 56/687 (8.2%)
0/72 (0.0%) 6/706 (0.8%) 2/395 (0.5%) 4/383 (1.0%)
74/295 (25.1%)
15/294
(5.1%)
Placental infarction ≥10% <10%
163/443 (36.8%)
(9.5%)
3/368 (0.8%) 1/118 (0.8%) 1/230 (0.4%) 1/188
(0.5%) (13.6%)
(5.7%) (39.3%)
(6.7%) (4.1%)
55/336 (16.4%) 19/113 (16.8%) 42/209 22/301 (7.3%) 6/103 (5.8%) 14/185
(20.1%) 24/176
(7.6%) 9/159 (25.2%) 46/117
(5.1%) 13/194 (3.8%) 8/193
66/200 (33.0%) 20/78
21/380 (5.5%) 10/122 13/380 (3.4%) 6/121
(25.6%) 28/111 (8.2%) 12/237
(5.0%) 9/237
27/391 (6.9%) 32/368 (8.7%)
43/354 (12.1%) 56/366 (15.3%)
6/56 (10.7%) 39/584 (6.7%) 20/321 (6.2%) 25/319 (7.8%) 6/30 (20.0%) 119/394 (30.2%) 51/193 (26.4%) 74/231 (32.0%)
1/75 (1.3%) 37/732 (5.1%) 20/410 (4.9%) 18/397 (4.5%) 2/75 (2.7%) 23/731 (3.1%) 9/409 (2.2%) 16/397 (4.0%)
2/66
(3.0%)
97/654
(14.8%)
Absent
IUGR
Absent
Gestational age
≥34 weeks <34 weeks 49/208 (23.6%) 190/532 (35.7%)
3/311 (1.0%) 32/292 (11.0%)
15/246 (6.1%) 37/141 (26.2%)
11/322 (3.4%)
3/464 (0.6%) 2/229 (0.9%) 4/549 (0.7%) 67/425 (15.8%) 20/204 (9.8%) 79/516 (15.3%)
28/392 (7.1%) 12/182 (6.6%) 33/458 (7.2%) 88/283 (31.1%) 24/101 (23.8%) 101/323 (31.3%)
27/482 (5.6%) 6/237 (2.5%) 32/570 (5.6%)
9/321
(2.8%) 16/482
(3.3%)
4/237 (1.7%) 21/569 (3.7%)
Placental weight percentile ≥10% <10% 82/217 (37.8%) 61/180 (33.9%)
8/220
(3.6%)
(9.5%)
120/351 (34.2%)
44/463
48/116 (41.4%)
51/539
22/353 (6.2%)
16/121 (13.2%)
16/221 (7.2%)
10/185
(5.4%)