Page 105 - Pro-active Management of Women’s Health after Cardiometabolic Complicated Pregnancies

Risk factor
Potentially modifiable risk factors
Systolic blood pressure (mmHg) Diastolic blood pressure (mmHg) Total cholesterol (mg/dl) HDL-Cholesterol (mg/dl)
Body mass index (kg/m2) Smoking (%)
Diabetes mellitus (%) Treatment for hypertension (%)
Non-modifiable risk factors
Familial CVD (<60y) (%)
Differences of risk factors after preeclampsia compared to controls* Median (IQR)
Effect of lifestyle interventions **
3.2 Effect of Lifestyle Interventions after Preeclampsia| 103
(values not shown).
In step 2d we used the risk prediction models found in step 1c to calculate
the odds-ratios of cardiovascular risk between women with a history of preeclampsia with or without lifestyle interventions, based on the differences of cardiovascular risk factors as provided in step 2c. The interquartile range in step 2c was used to calculate a confidence interval of the odds-ratios.
Table 3.2.1. Differences in cardiovascular risk factors in women 1 to 30 years after preeclampsia compared to controls without preeclampsia and estimated effects of lifestyle interventions programs.
7.5 (6.3-10.5) -2.4
7.0 (5.0-9.0) -1.8 11.5 (5.0-18.0) -2 0.0 (-1.5-0.0) 0 2.8 (1.8-3.0) -1.0% -10.9% (-18.0%-5.0%) -2.2% 1.7% (0.0%-3.0%) No 15.4% (12.3%-22.6%) No
22.2% (21.8%-26.3%) 0.5 (0.42-0.59)
(hs-)CRP (mg/l)
IQR = Interquartile Range, CVD = cardiovascular disease, CRP = C-reactive protein
Median
(IQR)
(-5.7– -1.3) (-4.5 – -0.9) (-16 – -2)
(-3 – -1) (-3.6% – 0.0%) (-7% – -0.7%) Data
Data
*Based on reported studies listed in table 3.2.3.
**Paired analysis before vs. after interventions, based on reported studies listed in table 3.2.4.
RESULTS
Cardiovascular risk after preeclampsia
The search in Step 1a resulted in 878 articles. As shown in figure 3.2.2, 13