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                                    Effect of periapical surgery on oral health-related quality of life1317significantly higher OHIP-14 score on the first 2 postoperative days compared to the older patient groups. Figure 1 shows the mean OHIP-14 scores per location. No significant interaction effect between time and OHIP-14 score was found for anterior teeth, premolars, and molars in the upper or lower jaw. Comparing the second molar region with the other locations, no significant differences were found during the week for the mean OHIP-14 scores during the first 3 days (day 1, p=0.84; day 2, p=0.34; day 3, p=0.27).Figure 1: Mean OHIP-14 score per location during the 1st postoperative week. Error bars indicate SD.-5051015202530Day 1 Day 2 Day 3 Day 4 Day 5 Day 6 Day 7OHIP-14Postoperative daysMean OHIP-14 per locationAnterior Maxilla Premolar Maxilla Molar MaxillaAnterior Mandible Premolar Mandible Molar MandiblePain scoresRepeated measures were used to determine mean scores over time for pain from postoperative day 1 to 7. Repeated measures ANOVA was used to analyze mean NRS scores collected each day during the first postoperative week (Table 2). We found a significant effect for the repeated measurements (F(6, 792) = 61.3, p < 0.001). Subsequent pairwise comparisons showed that the mean NRS scores decrease significantly throughout the week. Only the mean scores from day 3 and day 4 did not differ significantly (p=0.15), whereas all the mean scores on the other days differed significantly from each other (p<0.05).Women and smokers experienced significantly more pain during the first 3 days. Younger patients had a higher pain score compared to older patients on the first postoperative day. We found no significant interaction effect during 
                                
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