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e-TMJ replacement: Clinical analysis26910IntroductionExtended temporomandibular joint (TMJ) prostheses replace not only joint components but also adjacent mandibular and/or temporal bone defects.(1) We recently shifted from autologous to alloplastic replacement for a number of segmental mandibular defects, considering autologous replacement as a salvage procedure for implant failure. A similar strategy was advocated in 1999 by Peckitt in oncological cases.(2) It was heavily criticized and did not become popular in the pre-three-dimensional (3D) printing era. We herein review our experience with total alloplastic extended TMJ replacement (eTMJR), describing intraoperative obstacles and deficiencies in occlusal and esthetic outcomes. Our experience may guide future reconstructive surgeries. Fig. 1: Rendered basilar view of the eTMJR of Case #2 showing its components. (A) Mandibular component three-dimensional printed out of Titanium Grade 23. (B) Cranial base part of the fossa component, three-dimensional printed out of Titanium Grade 23. (C) Caudal part of the fossa component, CNC-milled out of UHMWPE enriched with alpha-tocopherol and crosslinked using 100 Gy gamma irradiation. Note the posterior lip extending caudally. CNC=Computer numerical controlled; UHMWPE = Ultra-high-molecular-weight polyethyleneNikolas de Meurechy NW.indd 269 05-06-2024 10:15