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Chapter 6174ConclusionA significant increase in lymphocyte counts was seen in both samples treated with the DLC-coated and the uncoated condyle, although this increase was more significant in the uncoated system. A significant increase in macrophages was also observed in the tissue samples from the coated system, but none of the samples examined, showed any sign of ‘neo-synovitis’ caused by wear or infection. No adverse local tissue reactions were observed. We can conclude that these results are satisfying and warrant further investigation through human application, as we do not expect any adverse reactions based on these results. Nikolas de Meurechy NW.indd 174 05-06-2024 10:14