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Chapter 6168to the coated samples (24.6 ± 18.45). In comparison, a relatively low amount of lymphocytes was found in the sham peri-articular tissue (9.5 ± 5.2). In addition, analysis using the Bonferroni correction found a statistically significant difference in both groups, compared to the shamgroup. This significantly higher lymphocyte count was more pronounced in the uncoated tissues (p = 0.001), compared to the coated samples (p = 0.018). No significant difference was found between the uncoated and coated peri-articular tissue with respect to the concentration of lymphocytes.Fig. 2: Peri-articular tissue of the specimen revealing a high macrophage count. (hematoxylineosin stain, original magnification X 100). Green arro MacrophagesWhen evaluating the presence of macrophages in the samples (Fig. 5), the sham tissues again show the least amount of macrophages (7.4 ± 10.36). The coated system’s tissues have a higher number of macrophages (22.15 ± 25.31) compared to the uncoated samples (17.76 ± 21.16), but this difference was not significant (p = 0.405). However, the coated group showed a significantly higher number of macrophages compared to the sham-group (p = 0.019), while the uncoated group did not (p = 0.141). The amorphous material that was found during dissection revealed to contain large amounts of hemosiderin (Fig. 3) and clusters of erythrocytes. Nikolas de Meurechy NW.indd 168 05-06-2024 10:14