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Animal experiment: Inflammatory cell response evaluation1696Fig. 3: Peri-articular tissue showing lymphocytes, debris, hemosiderin and a capillary present. (hematoxylin-eosin stain, original magnification X 100). Green circle: Capillary Red Circle: Lymphocytes Orange Circle: Debris Blue Circle: HemosiderinDiscussionGiven the severe adverse inflammatory reaction observed in patients treated with the Vitek-Kent replacement system (1,6,8), which had a significant impact on the use of TMJR with a near abandonment of the treatment method during several years, we aimed to provide a quantitative analysis of the inflammatory cell types found in sheep treated with a novel TMJR system, developed by CADskills BV (Ghent, Belgium), to determine its suitability for human implantation. Nikolas de Meurechy NW.indd 169 05-06-2024 10:14