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Chapter 5
Appendix 11 Baseline characteristics stratified by pretreatment sarcopenia. P values shown for linear-by-linear approximation of the Pearson’s Chi-square testb or Fisher’s exact Testc.
Mann-Whitney U testa,
< .001c
.095a 1.000b
< .001a .112b
.031b
.287b
.048c .090c
.090b
.041c .411c
No sarcopenia N = 59
Sarcopenia N = 49
P value
Gender Male Female
Age at baseline Median (range)
57 (97)
2 (3)
61 (39-81) 29 (49)
21 (36)
6 (10)
3 (5)
26 (18-44) 22 (37)
31 (53)
6 (10)
19 (32)
16 (27)
16 (27)
8 (14)
8 (14)
15 (25)
34 (58)
2 (3)
20 (34)
39 (66)
14 (25)
43 (75)
2
27 (46)
0 (0)
9 (15)
23 (39)
53 (90)
6 (10) 54 (96) 2 (4)
3
16 (33)
33 (67)
63 (47-79) 24 (49)
16 (33)
8 (16)
1 (2)
23 (17-35) 13 (27)
26 (53)
10 (20)
8 (16)
14 (29)
13 (27)
14 (29)
4 (8)
9 (18)
35 (71)
1 (20
8 (16)
41 (84)
19 (41)
27 (59)
3
12 (24)
3 (6)
8 (16)
26 (53)
36 (74)
13 (27) 44 (92) 4 (8)
1
ACE-27
BMI Median (range) Oropharyngeal
tumor site
T classification
N classification
AJCC stage HPV
Treatment modality
Modified diet at t0 (FOIS < 7)
Trismus at t0
0 1 2 3
Base of tongue Tonsil
Other
T1
T2
T3
T4
N0
N1
N2
N3
III
IV Negative Positive Unknown RT
RT unfit for RT+ RT + cetuximab RT + cisplatin No
Yes
No
Yes Unknown
NB: Not all percentages sum up exactly to 100% due to
rounding.
Abbreviations: BMI = body mass index, HPV = human papilloma virus, other =
vallecula or pharyngeal arch, RT = radiotherapy, sarcopenia = skeletal muscle mass below 43.2 cm2/m2.
soft palate, uvula, oropharyngeal wall,