Page 142 - Functional impairment and cues for rehabilitation of head and neck cancer patients -

140
Chapter 5
Appendix 9 Baseline characteristics stratified by HPV status. P values shown for Mann-Whitney approximation of the Pearson’s Chi-square testb or Fisher’s exact Testc.
U testa, linear-by-linear
.366c
.511a .151b
.001a .031a .090c
.198b <.001b
.026b
.336c .005b
.001c .175c
HPV -
n = 33
HPV +
n = 70
P value
Gender Male Female
Age at baseline Median (range)
20 (61)
13 (39)
62 (44-75) 14 (42)
13 (39)
3 (9)
3 (9)
24 (17-33) 41 (27-54) 14 (42)
19 (58)
10 (30)
15 (46)
8 (24)
1 (3)
7 (21)
15 (46)
10 (30)
6 (18)
9 (27)
18 (55)
0 (0)
10 (30)
23 (70)
6 (18)
1 (3)
18 (55)
8 (24)
20 (61)
13 (39) 28 (90) 3 (10) 2
50 (71)
20 (29)
62 (39-79) 38 (54)
24 (34)
7 (10)
1 (1)
26 (17-44) 45 (22-64) 43 (61)
27 (39)
24 (34)
40 (57)
6 (9)
26 (37)
21 (30)
11 (16)
12 (17)
5 (7)
13 (19)
49 (70)
3 (4)
15 (21)
55 (79)
32 (46)
1 (1)
30 (43)
7 (10)
64 (91)
ACE-27
BMI Median (range) SMM Median (range) Sarcopenia
Oropharyngeal tumor site
T classification
N classification
AJCC stage
Treatment modality
Modified diet at t0 (FOIS < 7)
Trismus at t0
0 1 2 3
No
Yes
Base of tongue Tonsil
Other
T1
T2
T3
T4
N0
N1
N2
N3
III
IV
RT
RT unfit for RT+ RT + cetuximab RT + cisplatin No
Yes
No
Yes Unknown
6 (9) 66 (97) 2 (3)
2
NB: Not all percentages sum up exactly to 100% due to
rounding.
Abbreviations: BMI = body mass index, HPV = human papilloma virus, other = vallecula or pharyngeal arch, RT = radiotherapy, sarcopenia = SMM below 43.2
soft palate, uvula, oropharyngeal wall, cm2/m2, SMM = skeletal muscle mass.