Page 123 - Bladder Dysfunction in the Context of the Bladder-Brain Connection - Ilse Groenendijk.pdf

2. Patients with a higher UDI-6 score will have a higher OAB-q SF symptom bother score.
3. Patients with a higher ICIQ-OAB Q (questions) score will have a higher OAB-q SF symptom bother score.
4. Patients with a higher ICIQ-OAB BS (bother scale) score will have a lower OAB-q SF HRQOL score.
5. Patients with a lower EQ-5D-5L index value and patients with a lower EQ-5D-5L VAS will have a lower score on the OAB-q SF HRQOL.
Floor and ceiling effects
Floor and ceiling effects were considered if more than 15% of the respondents would achieve the lowest or highest possible score.15 The floor and ceiling effects were cal- culated for symptom bother and HRQOL scores at baseline in the patient and in the reference group.
Statistical method
A sample size of at least 50 participants was considered adequate for validation of ques- tionnaires,15 thus we aimed to include a total of 100 patients, 50 in the patient group and 50 in the reference group. Continuous data are presented as mean, standard deviation (SD). The Student’s t-test and Chi-square test for continuous and categorical variables, respectively, were used evaluating differences between patient and reference group. Statistical analyses were performed using SPSS version 24.0 (IBM Corp., Armonk, NY, USA). Statistical significance was defined as P-Value <0.05.
RESULTS
In total, 103 participants were included in the study. In the patient group 56 patients signed an informed consent, of whom 52 patients completed the questionnaires at both time points. Four patients did not return the second questionnaire and were therefore excluded from the analyses. The reference group consisted of 51 participants who com- pleted the questionnaires at one time point. Table 1 displays the patient characteristics and the baseline scores of the four questionnaires.
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The validation of the Dutch OAB-q SF questionnaire 121