Page 148 - Reconstructive Techniques in Musculoskeletal Tumor Surgery
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                                Chapter 7
100, 31 patients at risk), 59% (95% CI 41 to 78, 15 patients at risk) and 46% (95% CI 26 to 66, ten patients at risk), respectively ( gure 3).
Figure 3. Kaplan-Meier curve for survival of the reconstruction, with failure for all reasons as the endpoint (red line), failure for non-oncological reasons (mechanical reasons and infection) as the endpoint (blue line) and failure for mechanical reasons as the endpoint (green line).
Systematic literature review
After review of 244 titles, 110 abstracts were screened, of which 82 full-text articles were subsequently assessed. This resulted in further exclusion of 51 papers, leaving 31 studies available for review ( gure 4)9, 14-19, 21-25, 37-55. Only  ve studies (16%) were level III evidence; the remainder (26/31, 84%) were level IV (supplementary material). Critical appraisal demonstrated that only nine (30%) of studies properly reported on eligibility criteria and sources and methods of patient selection ( gure 5). The 31 included studies reported on a total of 781 reconstructions in 769 patients.
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