Page 150 - Reconstructive Techniques in Musculoskeletal Tumor Surgery

Chapter 7
Figure 5. Result of the critical appraisal of studies included in the systematic review. Low reporting of selected criteria increases the risk of bias.
Overall reported rates of failure, fracture and infection were 27% (141/514), 20% (100/514) and 10% (52/514), respectively. Mean follow-up ranged from 24 months to 16 years. With the distal femur as the reference, we compared complication rates between di erent reconstruction sites. The risk of failure was lowest for the distal radius (OR 0.3, 95% CI 0.1 to 0.6). While the risk of fracture was signi cantly higher for the proximal humerus (OR 4.1, 95% CI 2.2 to 7.7) and proximal tibia (OR 2.2, 95% CI 1.3 to 4.4), the risk of infection was signi cantly higher for the proximal tibia (OR 2.2, 95% CI 1.1 to 4.3) and signi cantly lower for the distal radius (OR 0.1, 95% CI 0.0 to 0.8) (table 3). Results of studies that reported on at least 20 reconstructions are detailed in the supplementary material; many studies did not report the length of the graft. As a result of a lack of detailed description, we were not able to comment on an association between the type of osteosynthesis and the occurrence of complications.
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