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Of the 15 allografts that were followed for more than ve years (39%), ve (33%) failed after more than ve years post-operatively. Failures were salvaged with endoprostheses in 12 patients (32%; eight knee and three shoulder arthroplasties) and with an arthrodesis in two (5%; both at the wrist). Ablative procedures were undertaken in six patients (16%).
Osteoarticular allografts
Figure 2. Conventional anteroposterior and lateral radiographs, taken 15 years after resection of the proximal humerus for a low-grade osteosarcoma in a 46-year-old female patient. The allograft was xed to host bone using a plate. A bular strut graft can be identi ed in the intramedullary canal. Later, a transhumeral amputation was performed for a soft-tissue recurrence.
Estimated median allograft survival was 5.7 years (95% CI 0.4 to 11.1), when 22 patients were at risk for failure. With failure for any reason as the endpoint, survival rates at two, ve and ten years were 89% (95% CI 79 to 99, 30 patients at risk), 52% (95% CI 34 to 70, 15 patients at risk) and 41% (95% CI 23 to 59, ten patients at risk). With failure for mechanical reasons as the endpoint, these were 97% (95% CI 91 to
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