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                                    Chapter 5104DiscussionOur study aimed to examine whether PTS is correlated to either ATT or rTR during high-demand activities. The main finding was little (if any) to weak correlation between dynamic ATT and PTS, both before and after ACL reconstruction. By studying subjects using an in vivo motion-capture system, the dynamic forces of the muscles surrounding the knee joint were enabled, in contrast to what happens when measuring passive ATT. The influence of muscle activity may have led to a weak correlation between PTS and dynamic ATT in our study. Earlier studies show a correlation between PTS and ATT in a passive situation, and particularly that an increase in PTS leads to increased passive ATT.8-10,23,24,27,28,33,34 This previously observed correlation between PTS and passive ATT might be the sole representation of the mechanical interaction between the femur and the tibial slope, as explained by Dejour and Bonnin.10 Our study suggests that muscular activity enables subjects to compensate for anatomical factors such as PTS by moderating their muscle activation patterns and kinematics when studied during high-demand activities. Dynamic ATT, as measured in our study, is clinically more relevant than passive ATT, as the clinical feeling of giving way is experienced during high-demand activities.Muscle forces may be able to reduce dynamic ATT in ACL deficiency and after ACL reconstruction. We indeed found that the measured values for both dynamic rTR and ATT seemed lower in ACL-deficient knees and ACL-reconstructed knees compared to their contralateral intact limbs, although this difference was not significant. This may be explained by reduced quadriceps activity of the injured limb, which increases hamstrings-to-quadriceps ratio (HQ ratio). As shown in a 3D computer model by Shelburne et al., reducing quadriceps force can lower ATT in the presence of ACL deficiency.29 This theory is referred to as the quadriceps avoidance pattern. Moreover, computer models showed that an increase in hamstrings activity, also leading to an increased HQ ratio, likewise reduces the dynamic ATT.29,31 Although the theory of altered muscle activation to reduce dynamic ATT is supported by several authors2,16,21,29, it has been refuted by Keizer et al.18, who studied healthy subjects with an intact ACL in vivo. In their study, subjects with lax knees on instrumented Lachman Mark Zee.indd 104 03-01-2024 08:56
                                
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