Page 72 - Development of Functional Scaffolds for Bone Tissue Engineering Using 3D-Bioprinting of Cells and Biomaterials - Yasaman Zamani

void size scaffold (Fig. 9b). Average and maximum fluid pressure in the 0.3-0.6 gradient scaffold were higher than in the 0.6 homogeneous scaffold, and the 0.3-0.6-0.9 gradient scaffold was similar to the 0.6 homogeneous scaffold.
Figure 9. Finite element modeling of fluid pressure distribution and magnitude as a result of fluid flow inside the 3D- printed PCL scaffolds with different void size (0.3 mm, 0.6 mm, 0.9 mm, 0.3-0.6 mm, and 0.3-0.6-0.9 mm). (a) 3D, front, back, top, and bottom view of fluid pressure distribution and magnitude on the strands surface as a result of inlet fluid flow inside the 3D-printed scaffolds. For the homogeneous-structured scaffolds, fluid pressure magnitude decreased with increasing scaffold void size. Fluid pressure magnitude was more homogenous at higher void size compared to lower void size scaffolds. Fluid pressure was higher in the upper half compared with the lower half of the scaffolds for both the homogenous and gradient scaffolds. (b) Average and maximum fluid pressure was highest in the 0.3 mm void size scaffold and lowest in the 0.9 mm void size scaffold. Average and maximum fluid pressure in the 0.3-0.6 gradient scaffold were higher than in the 0.6 homogeneous scaffold, and the 0.3-0.6-0.9 gradient scaffold was similar to the 0.6 homogeneous scaffold.
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