Page 83 - THE EVOLUTION OF EARLY ARTHRITIS AND CARDIOVASCULAR RISK Samina A. Turk

Traditional cardiovascular risk factors
AN UNFAVORABLE BODY COMPOSITION
HDL, mmol/l
LDL, mmol/l
TChol: HDL ratio
Systolic BP, mmHg
Diastolic BP, mmHg
Current smoking 25 Statin use 15 Antihypertensive use 27
Results are expressed as mean (SD), percentages, or median (25-75th percentile). 4 ACPA: anti-citrullinated protein antibody, BP: blood pressure, DAS28: disease activity
score of 28 joints, ESR: erythrocyte sedimentation rate, HAQ-DI: health assessment questionnaire disability index, HDL: high-density lipoprotein, IQR: interquartile range,
LDL: low-density lipoprotein, mm/hour: millimetre/hour, mmHg: millimetre mercury, mmol/l: millimole/liter, n:number, NSAID: non-steroidal anti-inflammatory drugs, RA: rheumatoid arthritis, RF: rheumatoid factor, SD: standard deviation, SJC28: swollen joint count of 28 joints, TChol: total cholesterol, TJC28: tender joint count of 28 joints
Body composition (Fig 1, Table 5)
Compared to controls, BMI and FMI were 4% higher (p<0.01) in arthritis females, with a trend for more obesity (p=0.07). The percentage of fat distributed to the trunk was also higher, but the android and gynoid fat mass ratio was similar. ALMI was 5-7% lower in both sexes, and a low muscle mass for their age was 4-5 times more common (in females 5.0% vs 1.3%, and in males 8.2 vs 1.5%, p<0.01)(Table 5 and Fig 1).
Figure 1. Prevalence of a low muscle mass for age in early arthritis patients compared with non-arthritis controls
1.4 ( 0.5) 3.2 ( 0.9) 4.0 ( 1.3)
144 (22) 84 (12)
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