Page 82 - THE EVOLUTION OF EARLY ARTHRITIS AND CARDIOVASCULAR RISK Samina A. Turk

CHAPTER 4
50-59 years
60-69 years
70-86 years
Number Mean females in kg/m2
453 7.0 (0.9)
360 6.9 (0.8)
67 7.0 (0.8)
Cut off females in kg/m2
<5.3
<5.3
<5.4
ALMI: appendicular lean mass index, n: number, SD: standard deviation
RESULTS
Patient characteristics
A total of 317 early arthritis patients (mean age 61, 69% female) were matched with 1268 non-arthritis controls, see Table 3. Almost all patients were Caucasian; five were Asian, four African. Most patients (84%) fulfilled the American College of Rheumatology (ACR)/ European League Against Rheumatism (EULAR) 2010 criteria(32). Mean DAS28 was 5.0 (SD 1.4) points and 67% were seropositive for RF and/ or ACPA, see Table 4.
Table 3. Demographics
Early arthritis patients, n=317
Non-arthritis controls, n=1268
31
61 ( 8) 169 ( 9) 78 (15)
Gender, males 31 Age, years 61 Length (cm) 168 Weight (kg) 79
( 7) ( 9) (16)
Results are expressed as mean (SD) or percentages. Cm: centimeters, kg: kilograms
Table 4. Disease activity and traditional cardiovascular risk factors in early arthritis patients, n=317
Disease activity
DAS28 5.0 ( 1.4)
SJC28 6
TJC28 5
ESR in mm/hour 27
HAQ-DI 1
Symptom duration, months 7 ( 3 - 22) RF positive 55
ACPA positive 58
NSAID use 36
Traditional cardiovascular risk factors
TChol, mmol/l 5.2 ( 1.0) Triglycerides, mmol/l 1.2 ( 0.9- 1.6)
table continues
( 3 - 10) ( 2 - 10) (15 - 46) ( 1 - 2)
80