Page 140 - Fluorescence-guided cancer surgery

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Chapter 9
Table 1. Demographic and baseline characteristics of ovarian cancer patients
1 71
2 51
3 59
4 61
5 64
6 71
7 71
8 78
9 57
10 52
11 42
12 73
Primary Primary Staging Interval
Primary
Primary Primary Interval Interval Interval Primary Staging
debulking debulking
debulking debulking
debulking debulking debulking debulking debulking debulking
Serous adenocarcinoma
Endometroid type adenocarcinoma
Endometroid type adenocarcinoma
Serous adenocarcinoma of endometrium
Borderline serous adenocarcinoma
Serous adenocarcinoma
Serous adenocarcinoma
Serous adenocarcinoma
Serous adenocarcinoma
Serous adenocarcinoma
Mucinous adenocarcinoma Endometroid type adenocarcinoma
3c Yes Yes Yes 3b Yes Yes Yes 2c No Yes Yes
4 Yes Yes Yes
3b Non- Yes Yes invasive
implants
3c Yes Yes Yes 3b Yes Yes Yes 3c Yes Yes Yes 3c Yes Yes Yes
4 Yes Yes Yes 3c Yes No No 2b No Yes Yes
For breast cancer, a total of 53 potentially eligible breast cancer patients were selected for characterization of FRα status on preoperatively obtained biopsies. Samples of six patients stained positive for FRα (11%). Of the 6 patients, 2 patients eventually did not meet the inclusion criteria and 1 patient declined participation. Three patients were included in the study and their characteristics are provided in Table 2.
Table 2. Demographic and baseline characteristics of breast cancer patients
1 54 BCS
2 61 BCS
3 53 Mastectomy
IBC NST
Metaplastic carcinoma
IBC NST
19 Neg Neg Neg 42 Neg Neg Neg
23 Pos Pos Neg
Yes, 9mm Yes Yes* No Yes Yes
No Yes Yes
Abbreviations: BCS, Breast Conserving Surgery; IBC, in ltrative breast cancer; NST, No Special Type
* Tumor successfully identi ed in resection specimen. SLN metastasis not identi ed due to lack of tissue penetration.
Patient ID Age
Patient ID Age
Surgical procedure
Diagnosis
Surgical procedure
Tumor size in mm
Diagnosis
ER status PR Status
HER2 Status
SLN metastasis
Metastases identi ed
Tumor FRa+
Tumor FRa+
Fluorescence imaging successful
Fluorescence imaging successful
FIGO stage