Page 159 - Assessing right ventricular function and the pulmonary circulation in pulmonary hypertension Onno Anthonius Spruijt

Figure 4: Correlations between native T1-values of the interventricular insertion regions and RVEDVI, RVESVI, RVEF and RAP in PH patients. Native T1-values of the interventricular insertion regions of PH patients were significantly related to RVEDVI, RVESVI, RVEF and RAP. RVEDVI = right ventricular end-diastolic volume index; RVESVI = right ventricular end-systolic volume index; RVEF = right ventricular ejection fraction; RAP = right atrial pressure.
Discussion
This is the first study using the native T1-mapping technique to characterize the myocardium in precapillary PH patients. In PH patients, native T1-values of the interventricular insertion regions were significantly increased compared to the native T1-values of the RV free wall, LV free wall and interventricular septum. Furthermore, native T1-values of the interventricular insertion regions were related to disease severity.
Increased Native T1-values of the interventricular insertion regions
LGE studies in PH showed the late enhancement of the interventricular insertion regions and it has been suggested that this phenomenon most likely reflect locally increased focal fibrosis [2-5].
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