Page 96 - Risk quantification and modification in older patients with colorectal cancer
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Chapter 5
density were Q1 men: <23.21 HU, women: <20.08 HU; Q2 men: 23.21-30.26 HU, women: 20.08-25.42 HU; Q3 men: 30.26-33.18 HU, women: 25.42-31.22 HU; Q4 men: >33.18 HU, women: >31.22 HU. Baseline characteristics with stratification based on preoperative use of a mobility aid can be found in Appendix A.
Table 1 Baseline characteristics
Skeletal Muscle Mass (quartiles)
All Q1 patients
Total number of patients (n) 174 43
Mean age (SD) 78.0 5.1 78.4 (5.1) Gender (%)
Male 89 (51) 22 (51) Female 85 (49) 21 (49) BMIa kg/m2
BMI < 25 79 (45) 27 (63) BMI ≥ 25 95 (55) 16 (37) Comorbidity (%)
Cardiac Comorbidity 9 (5) 18 (42) CCIb score ≥2 70 (40) 17 (40) Tumour location (%)
Colon 143 (82) 40 (93) Rectum 31 (18) 3 (7) Tumour stage (%)
I 50 (29) 7 (16) II 66 (38) 19 (44) III 58 (33) 17 (40) ASA score (%)
III or IV 48 (28) 17 (40) (Neo)adjuvant treatment
Neoadjuvant 9 (5) 0 chemoradiation
Adjuvant chemotherapy 28 (16) 5 (12) Type of surgery
Laparoscopic 114 (66) 29 (67) Open 60 (34) 14 (33) Functional parameters
Use of a mobility aidc
Yes 36 (21) 9 (21) No 136 (79) 33 (79) ADL Dependency (Katz ≥2)
Yes 9 (5) 3 (7) No 165 (95) 40 (93)
Q2 Q3
Q4 p
94
45 43 43
77.7 (5.3) 79 (4.9)
23 (51) 22 (51)
22 (49) 21 (49)
23 (51) 15 (35)
22 (49) 28 (65)
17 (38) 17 (40) 20 (44) 16 (37)
31 (69) 40 (93) 13 (29) 4 (9)
13 (29) 12 (28) 17 (38) 16 (37) 14 (31) 16 (37)
7 (16) 12 (28)
6 (13) 1 (2) 10 (22) 7 (16)
28 (62) 27 (63) 16 (36) 17 (40)
4 (9) 11 (26) 40 (91) 32 (74)
1 (2) 2 (5) 43 (96) 42 (98)
77 (4.9) 0.2
22 (51) 0.9 21 (49)
14 (33) 0.02 29 (67)
19 (44) 0.6 17 (40) 0.8
32 (74)
11 (26) 0.01
18 (42) 0.3 14 (33)
11 (26)
12 (28) 0.1
2 (5) 0.2 6 (14)
30 (70) 0.8 13 (30) 0.8
12 (28) 0.1 31 (72)
3 (7) 0.7 40 (93)
