Page 40 - Risk quantification and modification in older patients with colorectal cancer

Chapter 2
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Table 4B Model Performance and Risk of Bias for “Anastomotic leakage” Prediction Models
Author
Events Predictors Discr. (n) (n) AUC
Type Ref
Discr. Calibr. AUC
Participant Selection
Outcome Predictor M M
M M
L L
Attrition Analysis H M
H H
M M
H M
L M
L M
M M
Dekker et al. 15
10 11 0.95 External 27 46
0.65 NR CHART L 0.80
Pasic et al. 19
14 4 NR External1
1.0 NR CHART M
Frasson et al. 21
277 6 63 4 31 23 332 9 149 5
0.63 External 46 NR None - 0.82 None -
0.73 NR NOMO- L GRAM2
Hu et al. 22
CHART CHART NOMO-
L M M
L L M M L L L L
Rojas-Machando et al. 27
Rencuzogullari et al. 29
0.65
External1
NR
0.58 NR GRAM
Hoshino et al. 33
Internal
0.72 Plot NOMO- L GRAM
Development
Validation
Presentation
Risk of bias
0.72
NR, not reported; 1External validation published together with internal validation; Mode of presentation: 2 Including an online calculator.
Calibr, Calibration; Discr. Discrimination; H-L: Hosmer-Lemeshow Chi-square X2 (p-value); O:E expected/observed
ratio. NA, not applicable; NR, not reported; CI, 95%
Confidence Interval;
46
O:E 1.1