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Generaldiscussionandfutureperspectives19912Together,thefourpartsofthisthesisformthegeartrainthatrepresentsaclinicalprocessAlthoughthecareandtreatmentofcraniosynostosispatientsisthemainfocusofthisthesisotherclinicalimplementationsforplasticorthognathicandrenalsurgeryarepresentedEachoftheparts;diagnosis(1)planning(2)surgery(3)andevaluation(4)areconsideredasasinglegearYetforanoptimallyfunctioningprocessnotonlyshouldthegearsthemselvesworkproperlybuteachgear’sinteractionswiththeothergearsshouldalsobeseamlessThiscreatescoherenceandbringsthecompleteclinicalprocesstoahigherlevel ThisalsomeansthatanimprovementtoasinglegearcanhelptheentiresystemtoworkmoreefficientlyInthefinalchapterofthisthesistheindividualpartsaswellasthegeartrainasawholeareevaluatedInadditionthischaptershowshowfutureupdatesanddevelopmentscanstimulatethegearstoturnfasterandimprovetheentireclinicalworkflowPART1-DIAGNOSISThetreatmentofcraniosynostosisischaracterizedbymanyfollow-upmomentswherethecranialshapeisassessedandthepatient’sdevelopmentismonitoredcloselyEarlierresearchpresentedbythe3DLabNijmegenandothercentersconfirmsthepotentialof3Dstereophotogrammetryforsuchassessmentsgivenits fast acquisition timehigh accuracyreproducibility andlack ofionizingradiationInPart1ofthisthesistheapplicabilityof3DstereophotogrammetryforclinicalpracticeincraniofacialsurgerywasinvestigatedThepowerfulcombinationof3Dstereophotogrammetryandseveral3Danalysismethodshasallowedustomaketheevaluationofcranialshapeandgrowthmoreobjectiveandaccurate3DstereophotogrammetryhasmeanwhilebecomeacornerstoneofclinicalconsultationandisnowfullynestedinourclinicalworkflowSemi-transparent3Doverlaysand3Dcolor-codeddistancemapshaveprovedtobeexcellenttoolsduringclinicalconsultationandprovidethepatientstheirparentsandtheCFAteamwithrelevantinformation(Figure1)InsummarytheanswertotheresearchquestionCanthediagnosisandfollow-upofcraniosynostosisbeimprovedbytheimplementationof3Dstereophotogrammetryisaclear yes