Page 44 - Migraine, the heart and the brain

Chapter 2
42
Table 2. continued
Infratentorial hyperintensities, No. (%)
Controls (n = 83)
Migraine (n = 203)
P ValueA
Migraine Headache
Men , Prevalence Progression13
3(12) 1 (4)
9(16) 5(9)
.75 .66
4(16) 2(8)
5(15) 3(9)
>.99
Women Prevalence Progression13
2(4) 1 (2)
30 (21) 21 (15)
.002 .01
18 (28) 13 (20)
12(15) 8(10)
.06 .10
Posterior circulation territory infarctlike lesions,
No. (%)e Baseline
3(4)
11 (5)
.76
2(2)
9(8)
.12
9-y Follow-up
3(4) 0
18(9) 10(5)
.14 .07
6(7) 5(6)
12(11) 5(4)
.46 .75
New lesion
Anterior circulation or basal ganglia infarctlike lesions (nonposterior circulation territory), No. (%) Baseline
8(10)
15(7)
.63
6(7)
9(8)
.79
9-y Follow-up
11 (13) 3(4)
20 (10) 5(3)
.41 .69
12(11) 2(2)
8(9) 3(3)
.82 >.99
New lesions
Abbreviation: IQR, interquartile range, aP values are for differences between the control group and the migraine group and between those in the migraine group with and
without aura. k Progression of deep white matter hyperintensities is de ned as an increase in volume after 9 years (A between follow-up and baseline>0.01 mL); progression of infratentorial hyperintensities is de ned as an increase in size, number, or both, cHigh progression of deep white matter hyperintensities de ned as the upper 20th percentile of progression distribution, d For analyses of deep white matter hyperintensity progression, 2 women in the control group were excluded (leaving n = 55), because of missing baseline volumes due to software failures during lesion segmentations, Visual comparison revealed no progression between baseline and follow-up for these 2 women. eThe number of participants with 1 or more infarctlike lesions, Three of 10 participants who already had a posterior circulation territory infractlike lesion at baseline developed additional lesions between scans.
Without Aura (n = 89)
With Aura (n = 114)
P ValueA >.99