Page 121 - Functional impairment and cues for rehabilitation of head and neck cancer patients -

Table 1 Baseline characteristics of patients at t0, t1 and t2. P values shown for Kruskal-Wallis Testa, linear-by-linear approximation of the Pearson’s Chi-square Testb, Mann Whitney U testc or Fisher’s exact testd.
Functional outcomes after (C)RT for OPC
t0
n = 108
t1
n = 99
t2
n = 71
68 (69) 52 (73)
31 (31) 19 (27)
63 60 (39–81) (39–77)
46 (47) 39 (55)
35 (35) 26 (37)
14 (14) 3 (4)
4 (4) 3 (4)
25 26 (17-44) (17-44)
44 45 (22-64) (22-64)
53 (54) 44 (62) 46 (47) 27 (38) 33 (33) 25 (35)
54 (55) 35 (49) 12 (12) 11 (16) 23 (23) 19 (27) 30 (30) 19 (27) 25 (25) 20 (28) 21 (21) 13 (18) 11 (11) 8 (11) 22 (22) 13 (18) 63 (64) 48 (68) 3 (3) 2 (3) 25 (25) 18 (25) 74 (75) 53 (75) 31 (31) 18 (26) 64 (67) 51 (74) 4 2
36 (36) 26 (37) 3 (3) 2 (3)
17 (17) 11 (16)
43 (43) 32 (45)
81 (82) 66 (93) 18 (18) 5 (7)
0 0
P
value t0, t1, t2
.461b
.499a .357b
.791a .506a .402b
.819b
.832b
.794b
.931b .454b
.973b
.090b
Onlyt0 P Not P
available
n = 34
24 (71)
10 (29)
65 (49–78)
14 (41)
10 (29)
9 (27)
1 (3)
24 (49-78)
13 (38)
13 (38) 8 (24) 4 (12) 8 (24) 5 (15) 17 (50) 3 (9)
7 (21) 22 (65) 2 (6)
4 (12) 30 (88) 14 (47) 16 (53) 4
9 (27) 2 (6)
7 (21)
16 (47)
23 (72) 9 (28) 2
value included value t0, no t0 t0, no only available t0
t0 n = 84
Gender
Age at baseline
Median (range)
ACE-27
Male Female
0 1 2 3
73 (68)
35 (32)
63 (39–81)
53 (49)
37 (34)
14 (13)
4 (4)
25 (17-44)
44 (22-64)
59 (55) 49 (45) 35 (32)
57 (53) 16 (15) 27 (25) 30 (28) 29 (27) 22 (20) 12 (11) 24 (22) 69 (64) 3 (3) 28 (26) 80 (74) 33 (32) 70 (68) 5
39 (36) 3 (3)
17 (16) 49 (45)
89 (82) 19 (18) 0
.834d 54 (64) 30 (36)
.316c 62 (47-83)
.248b 37 (44) 30 (36) 13 (16)
4 (5) .127d
.888b 31 (37)
33 (39)
20 (24) .006b 22 (26) 28 (33) 14 (17) 20 (24)
.589b 6 (7) 14 (17)
62 (74)
2 (2) .102d 17 (20) 67 (80) .192d 29 (40) 43 (60)
12 .384b 33 (39)
6 (7) 12 (14) 33 (39)
.212d NA
.648d
.530c .442b
BMI Median (range) SMM Median (range)
Sarcopenia
Oropharyngeal tumor site
T classification
N classification
AJCC stage HPV status
Treatment modality
Modified diet at t0 (FOIS < 7)
No
Yes
Base of tongue
Tonsil Other T1
T2
T3
T4
N0
N1
N2
N3
III
IV Negative Positive Unknown RT
RT unfit for RT+
RT + cetuximab
RT + cisplatin
No
Yes Unknown
.685b
.791b
.205b
.394d .267d
.481b
5
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