Page 38 - Effects of radiotherapy and hyperbaric oxygen therapy on oral microcirculation Renee Helmers

Chapter 2
Table 3. Summary of arterial blood gas results. All parameters are presented as medians (25th-75th percentiles) and were temperature-dependent analyzed at 37°C. Corresponding normal arterial blood gas reference ranges from healthy animals obtained by point-of-care blood gas analyzers from literature2,13 † are provided for comparison; unfortunately arterial AnGap, Cl-, and Lac ranges derived from point-of-care blood gas analyzers were not reported, baseline reference ranges (minimum to maximum) from our animal group are presented.
pH
paO2 paCO2
HCO – 3
BE tHb sO2
Na+ K+
Ca2+
Cl– AnGap Glu
Lac
[AU] [mmHg] [mmHg] [mmol/L] [mmol/L] [mmol/L] [%]
[mmol/L]
[mmol/L]
[mmol/L]
[mmol/L] [mmol/L] [mmol/L]
[mmol/L]
T0: BL (FiO2: 21%)
7.49 (7.45-7.50) 71 (55-84) 40 (33-48) 30 (27-32) 5.8 (4.0-6.7) 7.5 (7.2-9.2) 95.5 (89.2-
98.2)
141 (133-142)
3.0 (2.7-3.2) 0.85 (0.65-1.35)
99 (98-108) 14 (11-15) 15.0 (8.2-16.0)
0.65 (0.63- 0.68)
T1 (FiO2: 55%)
7.51 (7.49-7.53) 184 (107-196)* 38 (32-44)
27 (26-33) 3.9 (2.8-8.6) 7.6 (7.4-8.3) 99.6 (99.4-99.7)*
142 (137-146)
2.8 (2.7-3.3)
0.71 (0.60-1.29)
102 (98-108) 15 (13-15) 12.7 (9.3-17.4)
0.65 (0.58-0.68)
NB
T2 (FiO2: 100%)
7.49 (7.48-7.51) 452 (335-521)* 42 (37-42)
31 (27-36) 6.3 (3.9-11.2) 8.1 (7.7-8.4) 99.7 (99.7-99.9)*
140 (138-143)
3.1 (2.8-3.3)
0.73 (0.50-1.18)
100 (98-101) 13 (10-13) 15.4 (11.8-18.1)
0.72 (0.69-0.75)
T3 (FiO2: 21%)
7.49 (7.48-7.51) 86 (75-98) 40 (38-47) 31 (28-35) 6.5 (5.0-9.8) 8.2 (8.0-9.2) 96.7 (95.8-98.6)
139 (136-141)
3.0 (2.8-3.2)
0.89 (0.71-1.15)
98 (97-101) 14 (13-15) 16.7 (14.0-19.9)
0.75 (0.75-0.84)
AnGap anion gap, BE base excess, BL baseline, FiO2 fraction of inspired oxygen, Glu glucose, HB hyperbaric, HCO3– bicarbonate, Lac lactate, NB normobaric, paO2 partial pressure of oxygen in arterial blood, paCO2 partial pressure of carbon dioxide in arterial blood, sO2 oxygen saturation, tHb total hemoglobin
*p<0.05 vs. T0, Friedman test
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