Page 122 - Effects of radiotherapy and hyperbaric oxygen therapy on oral microcirculation Renee Helmers

Chapter 6
tissue microvasculature and luminal blood flow. 16 clips were acquired from each patient, 4 clips per ROI. A total of 1632 clips were analyzed. No significant difference in Fd was observed between the time points [Table 2].
Table 1. Patient demographics.
Patient demographics [N=34]
Age
Gender Dental status
Co-morbidities
Diabetes Hypertension COPD
Intoxication
Smoking history Smoker
Cancer therapy
CRT Only RT
Site of radiation
Oral cavity Oropharynx Hypopharynx Nasopharynx Larynx
Other
Oral lesion presence
RT
Mean RT dosage buccal mucosa Mean RT dosage gingiva
Time since RT
HBOT
Prophylactic indication Therapeutic indication Number of sessions
Mean SD
[yrs]
[F:M] 12:22 [edentulous:dentate] 10:14
N (%)
1 (3%) 2 (6%) 2 (6%)
4 (12%) 8 (24%)
14 (41%) 20 (59%)
12 (35%) 12 (35%) 0 (0%) 4 (12%) 2 (6%) 4 (12%) 9 (26%)
[Gy] [Gy] [yrs]
N (%)
16 (47%) 18 (53%)
38 ± 13 51 ± 12 4 ± 5
32 ± 7
59 ± 12
CRT chemoradiotherapy; COPD chronic obstructive pulmonary disease; HBOT hyperbaric oxygen therapy, RT radiotherapy; SD standard deviation
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