Page 131 - Molecular features of low-grade developmental brain tumours
P. 131
Tumour Tumour mTOR
AED* size (mm) recurrence/ inhibitors Other clinical manififistations
regrowth
5
DYSREGULATION OF MMP/TIMP IN SEGA: MODULATION BY MIR-320D IN VITRO
yes NA yes yes yes
yes NA
yes yes NA yes yes yes yes
yes NA
yes yes
yes NA yes NA yes
yes
42 no u.k. no 31 no 40 no 30 no
20 no 5 no
5 yes 45 no 27 no 30 no 20 yes 40 no 30 no
30 no unknown unknown
30 yes 20 no
34 yes 20 no 18 no 37 no 60 no
66 no
no unknown
no
no
no
yes
(non responder) yes (responder)
no no no no no no no no
no no
no no
no no no no no
no
no other signs for TSC
cortical tuber, AML
cortical tuber
multiple SEGAs,cortical tubers, drug resistant epilepsy
tubers, minor psychomotor delay, SEN
renal cysts cortical tuber unknown
no other signs for TSC cortical tuber cortical tuber unknown
minor psychomotor delay
none cortical tuber
cortical tubers, autism, drug resistant epilepsy, behaviour problems (aggressivity) minor psychomotor delay, cortical tubers
unknown
cortical tuber cortical tuber, AML, autism SEN
cortical tuber, AML, autism
cortical tuber, AML, autism, FCD
129
