Page 159 - Coronary hemodynamics in acute myocardial infarction - Matthijs Bax

Time course of coronary flow capacity in STEMI
statistically significant difference between normal and mildly reduced CFC was observed for CFR (p < 0.001) and hAPV (p < 0.001), but not for bAPV (p = 0.077). At six-month follow-up, non-culprit vessel measurements were obtained in the same non-culprit vessel as during one-week follow-up: in 65 patients. Six months after AMI, CFC in the non-culprit vessel was normal in 92% and mildly reduced in 8% of patients. A statistically significant difference between normal and mildly reduced CFC was observed for CFR (p = 0.003), hAPV (p = 0.003) and HMR (p < 0.001).
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Figure 3. Time course of coronary flow capacity (CFC) in the culprit (a) and the non-culprit vessel (b) post primary percutaneous coronary intervention (PCI), at one-week and at six-month follow-up. In the culprit vessel, CFC improved significantly post PCI compared with one-week and six-month follow-up (p<0.001) and one-week compared with six-month follow-up (p=0.0013). In the non-culprit vessel, CFC improved post PCI compared with one-week and six-month follow-up, and one-week compared with six-month follow-up (all p < 0.001).
CFC improved significantly both in the culprit and the non-culprit vessel, when compared at baseline post PCI with one-week follow-up (p=0.036 and p<0.001), and one-week follow-up compared with six-month follow-up (p = 0.0013 and p < 0.001) (Figure 3; Supplementary file 5).
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