Page 28 - Physical activity in recipients of solid organ transplantation - Edwin J. van Adrichem

Chapter 2
Figure 1.
eart
and h
Mediation models of physical activity and cardiovascular mortality through cardiac ischemia (A) failure (B). e indirect e ect is quanti ed as path a times path b. e total e ect is calculated as
a*b+c’. Results
A total of 540 RTR (mean ± SD age: 51.3 ± 12.2, 54% male) were studied.
characteristics, transplantation history, and cardiac markers are presented in Table 1.
proBNP (r= -0.30,
p
<0.001), and Hs-TnT (r= -0.24,
p
<0.001) were all signi

e baseline
median (IQR) MET-min/day in the entire cohort was 117.1 (26.5; 294.3). RTR in the
inactive tertile performed a median (IQR) of 3.7 MET-min/day (0.1; 28.5), and the
moderate active and active tertile performed a median (IQR) of 117.1 MET-min/day
(74.6; 226.1) and 381.8 MET-min/day (234.0; 541.5), respectively. A total of 52% of the
participants complied to the PA guidelines. MR-proANP (r= -0.20,
p
<0.001), NT-

cantly
correlated with the PA level. Concentrations of cardiac markers showed a signi
decreasing trend (
p
=<0.001) according to increasing tertiles of PA (Figure 2).

cant and
e
Figure 2.
Cardiac markers per physical activity group (inactive/ moderate active/ active). Data presented as
median and interquartile range. MR-proANP, mid-regional pro-atrial natriuretic peptide; NT-proBNP, N-
terminal-pro brain natriuretic peptide; Hs-TnT, high sensitive troponine T. Tertiles of PA are strati

ed for
gender. MR-pr
oA
e dotted line represents the upper range of the normal value of the concerning marker. Data on NP was available in n=176, 168 and 169 per physical activity tertile, respectively.
26.