Page 64 - The role of advanced echocardiography in patients with ischemic heart disease - Rachid Abou

Chapter three. Age related left atrial remodeling
Table 4. Univariate and multivariate linear regression analyses to explore correlates of P-wave dispersion
Variable
Univariate analysis
Multivariate analysis
β
95% CI
p-value
β
95% CI
p-value
Gender 0.482
BMI (kg/m2) 0.281
Age (years) 0.226
Hypertension 4.362
Hypercholesterol- 1.058 emia
Diabetes mellitus 1.292 ACEi-ARBs 1.825 Beta-blocker 4.053 Statins 0.713
-1.917 to 2.881 -0.015 to -0.578 0.155 to 0.297 -1.929 to 6.794 -2.091 to 4.208
-2.475 to 5.058 -0.959 to 4.609 0.773 to 7.334 -2.349 to 3.776 -0.248 to -0.054 -0.106 to 0.209
0.054 to 0.143
0.693
0.063 <0.001 <0.001 0.509
0.501 0.198 0.016 0.647 0.002 0.524
<0.001
----- 0.091 0.161 2.012 -----
----- -1.838 1.925 ----- -0.025 -----
0.046
--------------- -0.213 to 0.394 0.074 to 0.248 -1.194 to 5.217 ---------------
--------------- -5.131 to 1.455 -1.486 to 5.336 --------------- -0.130 to 0.081 ---------------
-0.002 to 0.094
----- 0.558 <0.001 0.218 -----
----- 0.273 0.268 ----- 0.645 -----
0.058
LA reservoir strain (%)
LA volume, indexed (ml/m2)
PA-TDI (ms)
-0.151 0.051
0.099
ACEi= angiotensin converting enzyme inhibitor; ARB= angiotensin II receptor blocker; BMI= body mass index; CI= confidence interval; LA= left atrial; LV= left ventricular; TDI= tissue doppler imaging.
Table 5. Univariate and multivariate linear regression analyses to evaluate correlates of PA- tissue Doppler imaging.
Variable
Univariate analysis
Multivariate analysis
β
95% CI
p-value
β
95% CI
p-value
Gender
BMI (kg/m2)
Age (years)
Hypertension
Hypercholesterolemia
Diabetes mellitus
ACEi-ARBs
Beta-blocker
Statins
P-wave dispersion (ms)
LA volume, indexed (ml/m2)
LA reservoir strain (%)
2.846 0.808 0.637 11.194 7.308 8.094 10.363 5.561 6.514 0.513
0.525 -0.422
-2.463 to 8.155 0.157 to 1.458 0.485 to 0.789 5.758 to 16.630 0.356 to 14.260 -0.327 to 16.514 4.200 to 16.527 -1.761 to 12.884 -0.252 to 13.279 0.282 to 0.744
0.177 to 0.874 -0.630 to -0.214
0.292
0.015 <0.001 <0.001 0.039 0.060 0.001 0.136 0.059 <0.001
0.003 <0.001
----- 0.132 0.476 0.455 1.003 3.133 3.493 -1.314 -1.070 0.230
0.294 -0.089
--------------- -0.547 to 0.812 0.283 to 0.669 -6.775 to 7.686 -9.996 to 12.003 -5.869 to 12.135 -4.000 to 10.987 -9.102 to 6.473 -11.688 to 9.548 -0.005 to 0.465
-0.049 to 0.636 -0.326 to 0.147
----- 0.702 <0.001 0.902 0.858 0.494 0.360 0.740 0.843 0.055
0.093 0.458
ACEi= angiotensin converting enzyme inhibitor; ARB= angiotensin II receptor blocker; BMI= body mass index; CI= confidence interval; LA= left atrial; LV= left ventricular.
All these findings indicate that ageing was associated with slow LA conduction and
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