Page 65 - The role of advanced echocardiography in patients with ischemic heart disease - Rachid Abou

reduced LA compliance, suggesting the presence of increasing fibrosis of the LA wall.
On multivariate analysis, only age (β=0.161; [95%CI; 0.074 to 0.248], p<0.001) was independently associated with prolonged PWD (Table 4). In addition, increasing age
(β=0.476; [95%CI; 0.283 to 0.669], p<0.001) was the only independent determinant
of prolonged PA-TDI duration (Table 5). Finally, older age (β= -0.259; [95%CI; -0.345
to -0.174], p<0.001), larger body mass index (β=-0.582; [95%CI; -0.883 to -0.280], 3 p<0.001) and larger LA volume index (β=-0.117; [95%CI; -0.331 to -0.022], p=0.025)
were independently associated with more impaired LA reservoir strain (Table 6).
Table 6. Univariate and multivariate linear regression analyses to assess correlates of left atrial reservoir function.
Variable
Univariate analysis
Multivariate analysis
β
95% CI
p-value
β
95% CI
p-value
Gender
BMI (kg/m2)
Age (years)
Hypertension
Hypercholesterol- emia
Diabetes mellitus ACEi-ARBs Beta-blockade Statins
P-wave dispersion (ms)
LA volume, indexed (ml/m2)
PA-TDI (ms)
0.454 -2.080 to 2.978 -0.901 -1.207 to -0.595 -0.292 -0.364 to -0.219 -2.754 -5.374 to -0.134 -3.113 -6.407 to 0.182
-4.437 -8.457 to -0.416 -0.467 -3.445 to 2.510 -0.652 -4.135 to 2.831 -2.103 -5.321 to 1.115 -0.170 -0.279 to -0.061
-0.293 -0.460 to -0.126
-0.095 -0.141 to -0.048
0.724 ----- <0.001 -0.582 <0.001 -0.259 0.039 1.890 0.064 -0.494
0.031 -1.273 0.758 ----- 0.713 ----- 0.200 ----- 0.002 -0.031
0.001 -0.177 <0.001 -0.017
--------------- -0.883 to -0.280 -0.345 to -0.174 -0.748 to 4.528 -3.876 to 2.889
-5.314 to 2767 --------------- --------------- --------------- -0.138 to 0.075
-0.331 to -0.022 -0.065 to 0.032
----- <0.001 <0.001 0.160 0.744
0.536 ----- ----- ----- 0.562
0.025 0.496
ACEi= angiotensin converting enzyme inhibitor; ARB= angiotensin II receptor blocker; BMI= body mass index; CI= coinfidence interval; LA= left atrial; LV= left ventricular; TDI= tissue doppler imaging.
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