Page 41 - The role of advanced echocardiography in patients with ischemic heart disease - Rachid Abou

RESULTS
Global, level- and layer-specific values of LV longitudinal strain were compared between
patients with versus patients without cardiovascular risk factors or medications (Table 2 1). There were no statistically significant differences in LV GLS, level- and layer-specific longitudinal strain between groups and, accordingly, we investigated the effects of
ageing in the overall population.
Table 1. Characteristics for no cardiovascular risk profile versus patient with cardiovascular risk profile.
Cardiovascular risk profile
Variable
No (n=94)
Yes (n=314)
p-value
Age (years)
Men
BSA (m2)
BMI (kg/ m2) Cardiovascular risk factors Medication
Global longitudinal strain Basal
Mid
Apical
Endocardium Mid-myocardium Epicardium
54 ± 16 54 (57%) 1.9 ± 0.2 25 ± 3.4 0
0 -19.2 ± 2.0 -16.9 ± 2.4 -18.9 ± 2.1 -22.8 ± 4.0 -21.8 ± 2.4 -19.3 ± 2.3 -17.0 ± 1.8
59 ± 16 145 (46%) 1.9 ± 0.2 26 ± 4.2 314 (100%) 181 (58%) -18.8 ± 2.0 -16.7 ± 2.1 -18.8 ± 2.0 -22.6 ± 3.7 -22.2 ± 2.3 -19.0 ± 2.0 -16.6 ± 1.9
0.004 0.055 0.709 0.139 <0.001 <0.001 0.072 0.528 0.630 0.485 0.126 0.297 0.051
Data are presented as mean ± standard deviation or as number (percentage).
ACEi angiotensin-converting –enzyme inhibitor, ARB angiotensin II receptor blocker, BMI body mass index, BSA body surface area
Hypertension was defined as office blood pressure ≥140/90 mm Hg or previous pharmacological treatment. Hypercholesterolemia was defined as total cholesterol 190 mg/dl or previous pharmacological treatment. Diabetes mellitus was defined as fasting blood glucose ≥7.0 mmol/L, 2-h oral glucose tolerance test glucose ≥11.1 mmol/L, previous pharmacological treatment.
The clinical characteristics of the patients classified according to 5 age categories are presented in Table 2. There was a significant increase in the prevalence of hypertension, hypercholesterolemia and type 2 diabetes mellitus across the age categories, whereas family history of cardiovascular disease were more prevalent among younger and middle age groups (Table 2). The use of cardiovascular medications was more frequently noted in older groups (Table 2).
35