Page 27 - The role of advanced echocardiography in patients with ischemic heart disease - Rachid Abou

Figure 6. Research based apllications of speckle tracking echocardiography with two- dimensional echocardiography. The figure demonstrates left atrial (LA) strain analysis. The LA endocardium is manually traced in the apical 4-chamber view, and the region of interest is adjusted to fit the thickness of the LA wall. Strain curves for individual LA segments are illustrated. LA strain is measured as the peak global longitudinal strain during ventricular systole, which is indicated by the dotted line within the strain curves.
AIMS AND OUTLINE OF THIS THESIS
The objective of this thesis was to evaluate the role of advanced echocardiography for the risk stratification and possible treatment guidance of patient with ischemic heart disease.
In Part I, we gained more insight into left ventricular mechanics. We determined (near) normal reference values and gained better understanding of advanced echocardiographic parameters in subjects with no structural heart disease across a wide age range. Chapter 2 is predominantly focused on level and layer-specific LV GLS whereas Chapter 3 is mainly focused on left atrial parameters derived from advanced echocardiography and the conventional electrocardiogram. Part II, focusses on the role of advanced echocardiography in patients with ischemic heart disease. Chapter 4 evaluated the effect of guideline based therapy on LV systolic functional recovery. Chapter 5 provides more insight into LV mechanics and the value of multilayer LV GLS in adverse remodeling. Chapter 6 describes the prognostic value of layer-specific LV GLS in patients with mildly reduced or preserved LVEF. Chapter 7 investigates clinical
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