Page 89 - Let them speak Towards a patient reported outcome measure set for

PROs used in clinical trials and core outcome sets
Table 1. Unique PROs used in clinical trials and included in five condition-specific COSs.
PROs used in clinical trials PROs included in COSs
PRO PRO No. COS %
Frequency %* Quality of life 72 34 Cognitive functioning 4 80
Perceived health 55 26 Quality of life 3 60
Cognitive functioning
47 22 Communication 2 40
(attention, alertness)
Anxiety/stress 35 16 Pain (skin pain) 2 40
Depressive symptoms
32 15 Sleep 2 40
(suicide)
Mental functioning 20 9 Gastrointestinal
2 40
symptoms
Anger/irritability 17 8 Physical functioning 2 40
Physical (motor) functioning 16 8 Anxiety/stress 1 20
Communication 14 7 Upper extremity 1 20
Sleep 14 7 Respiratory symptoms 1 20
Participation 13 6 Mental functioning 1 20
Activity 12 6 Participation 1 20
Pain 8 4 Self-care 1 20
Vision 1 20
4
PRO, patient reported outcome; COSs, core outcome sets.
*Percentages are rounded.
PROs included in condition-specific COSs
The literature search resulted in 1.986 articles. No additional articles were
identified by reference list checking. A total of 1.975 articles were excluded
based on title and abstract. Five articles met the pre-defined inclusion
criteria after reviewing the full-text versions of the remaining 11 articles
(Figure 2). An overview of the study characteristics of the included studies
can be found in Additional file 3.
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