Page 292 - Prevention and Treatment of Incisional Hernia- New Techniques and Materials
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Chapter 14
of clinically evident mesh infection with transcutaneous migration of the prosthesis. At sacri ce, macroscopic infection of the mesh was present in 22 of 57 animals (39%). In Figure 2, the percentage of mesh infections per mesh group is shown. The mesh infection rate was signi cantly higher for crosslinked meshes compared with non-crosslinked meshes (70% vs 4%; P < 0.001). In 16 animals, the mesh was encapsulated by a large abscess, and in 6 animals, abscesses in parts of the mesh were found (Figure 3). No additional mesh infections were discovered by microbiological culture of the meshes performed during sacri ce.
Figure 2. Comparison of combined percentage (90 and 180 days) of mesh infection. Values are percentages of macroscopically infected meshes of surviving animals. * non-crosllinked and ยง crosslinked meshes.
Intra-abdominal or abdominal wall abscesses were found in 42% of all surviving animals at sacri ce. Most abscesses were located at the ligation of the cecal stump. There was no signi cant di erence in amount and size of intra-abdominally (non-mesh related) observed abscesses (P 5.321) between the meshes. Although when di erentiated between crosslinked and non- crosslinked meshes, more abscesses were observed in the animals with crosslinked meshes implanted (P =0.011).
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