Page 54 - Demo

Chapter 352similar after ACLR when measured during high-demand functional tasks, replicating sports activities, while a decrease is seen during low-demand tasks, as is seen in previous studies. This study aims to determine rTR before and after ACLR, assessed during low- and high-demand functional tests. MethodsDesign This trial was set up as a multicentre prospective cohort study. Martini Hospital and University Medical Center Groningen, both large teaching hospitals, served as recruiting centres. The study protocol was reviewed and approved by the Institutional Review Board of University Medical Center Groningen (registration ID 2015/524, UMCG trial register no. 201501098). The trial was registered in the Dutch Trial Register (NTR: www.trialregister.nl, registration ID NL7686).ParticipantsFrom June 2016 to June 2018 all patients diagnosed with ACL injury in one of the participating hospitals were consecutively screened for eligibility to participate in the study. Inclusion criteria were: (1) age 18-35 years, (2) unilateral ACL rupture confirmed by physical examination, (3) less than three months post-injury at time of diagnosis, (4) at least six weeks of conservative therapy, (5) intact contralateral knee on physical examination, (6) absence of concomitant injury to cartilage, bone, meniscus or other ligaments on MRI. Exclusion criteria were: (1) any history of fractures, osteotomy or previous ligament reconstructive surgery in the lower extremities or spine, (2) neurological conditions leading to musculoskeletal disorders, (3) any other musculoskeletal pathology of the lower limbs (i.e. concomitant ligamental injuries or meniscal injuries), (4) inability to complete questionnaires in Dutch.As presence or absence of any concomitant knee injury can influence the degree of tibial rotation; as injury to the menisci and anterolateral structures of the knee are known to play a role, we only included subjects without concomitant injury to the knee.Mark Zee.indd 52 03-01-2024 08:56