Page 125 - Recognizing axial spondyloarthritis - Janneke de Winter

THE PRE-SPA COHORT
Clinical examination
modified Schober, cm, mean (SD) modified Schober <4.5cm
Chest expansion, cm, mean (SD) Chest expansion <3.6cm
BASMI, 0-10, mean (SD) TJC > 0, 0-68 joints
SJC > 0, 0-66 joints MASES, 0-13, mean (SD) Dactylitis
Nail psoriasis
Psoriasis
Laboratory
CRP, mg/L, mean (SD)
CRP above 5 mg/L
ESR, mm/h, mean (SD)
ESR above 20 mm/h Calprotectin, ng/mL, mean (SD) Calprotectin above 715 ng/ml Imaging
Low grade sacroiliitis on X-ray
SpA abnormalities of the lumbar spine on X-ray
Syndesmophytes of the cervical spine on X-ray
Inflammatory lesions of the SIJ on MRI Inflammatory lesions of the spine on MRI
SpA criteria
mNY
ESSG
ASAS axSpA
ASAS peripheral SpA CASPAR
HLA-B27 positive (n=26)
5.85 (4.63) 3 (12) 6.24 (2.74) 1 (4)
2.04 (0.77) 5 (19)
0 (0)
6 (23)
0 (0) 0 (0) 0 (0)
2.37 (3.65)
3 (12)
6.68 (7.83)
2 (8)
309.39 (121.71) 0 (0)
2 (8) 0 (0)
1 (4)
6 (24) 0 (0)
0 (0) 6 (23) 5 (19) 0 (0) 0 (0)
HLA-B27 negative (n=25)
6.51 (6.71) 9 (32) 6.28 (2.23) 1 (4)
2.28 (0.74) 3 (12)
0 (0)
4 (16)
0 (0) 0 (0) 0 (0)
2.37 (3.32)
3 (12)
6.76 (6.58)
2 (8)
381.50 (130.00) 0 (0)
1 (4) 0 (0)
0 (0)
5 (20) 0 (0)
0 (0) 4 (16) 4 (16) 0 (0) 0 (0)
p-value
0.212 0.079 0.447 0.978 0.294 0.482 - 0.529 -
- -
0.763 0.960 0.502 1.000 0.048 -
0.556 -
0.997
0.735 -
- 0.529 0.765 -
-
ASAS, Assessment of SpondyloArthritis international Society; ASDAS, Ankylosing Spondylitis Disease Activity Score; axSpA, axial spondyloarthritis; BASDAI, Bath Ankylosing Spondylitis Disease Activity Index; BASFI, Bath Ankylosing Spondylitis Functional Index; BASMI, Bath Ankylosing Spondylitis Metrology Index; BMI, body mass index; CASPAR, ClASsification criteria for Psoriatic ARthritis; cm, centimeter; CRP, c-reactive protein; DMARD, disease modifying antirheumatic drugs; ESSG, European Spondyloarthropathy Study Group; ESR, erythrocyte sedimentation rate; FDR, first degree relatives; IBD, inflammatory bowel disease; HLA-B27, human leukocyte antigen-B27; kg, kilogram; MASES, Maastricht Ankylosing Spondylitis Enthesitis Score; m, meter; mm, millimeter;
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