Page 124 - Recognizing axial spondyloarthritis - Janneke de Winter

CHAPTER SEVEN
Table 3. Clinical characteristics, laboratory and imaging results of the HLA-B27 positive and HLA-B27 negative FDRs
HLA-B27 positive (n=26)
15 (58) 25 (96) 25.3 (5.5) 24.1 (3.1) 8 (31)
0 (0)
12 (46) 6 (23) 2 (10) 4 (15)
8 (46) 1 (4) 0 (0) 0 (0)
2 (8) 0 (0) 0 (0) 2 (8)
26 (100) 2 (8)
1 (4)
1 (4)
1 (4)
5.88 (8.95) 9.65 (13.29) 4.00 (7.47)
1.00 (1.05) 1 (4)
1 (4)
6 (23) 0.38 (0.60)
HLA-B27 negative (n=25)
10 (40) 25 (100) 26.3 (4.9) 22.9 (3.2) 6 (24)
0 (0)
17 (68) 5 (20) 0 (0)
1 (4)
12 (32) 0 (0)
0 (0)
0 (0)
0 (0) 1 (4) 0 (0) 0 (0)
25 (100) 0 (0)
1 (4)
5 (20)
0 (0)
7.52 (14.16) 11.48 (19.00) 6.64 (18.35)
1.35 (1,51) 2 (8)
0 (0)
7 (28) 0.49 (0.93)
Demographics
Male gender
Caucasian
Age, years, mean (SD)
BMI, kg/m2, mean (SD)
Current smoker
Use of DMARD, TNF inhibitor
or corticosteroids ever
History
Axial disease
Back pain
Inflammatory back pain
Buttock pain
Good response to NSAIDs
Peripheral disease
History of arthralgia
History of peripheral arthritis
History of enthesitis
History of dactylitis
Extra-articular disease
History of psoriasis
History of IBD
History of urethritis/diarrhoea
History of uveitis
Family history
Ankylosing spondylitis
Psoriatic arthritis
Psoriasis
Inflammatory bowel disease
Uveitis
Disease activity measurements
PhGA, 0-100mm VAS, mean (SD) PGA, 0-100mmVAS, mean (SD) Patient nocturnal pain, 0-100mm VAS, mean (SD)
BASDAI, 0-10cm, mean (SD)
BASDAI >4
ASDAS-CRP, mean (SD)
ASDAS-CRP ≥1.3
BASFI, 0-10cm, mean (SD)
p-value
0.211 0.327 0.396 0.248 0.753 -
0.119 0.791 0.161 0.176
0.305 0.327 0.327 -
0.161 0.308 - 0.161
- 0.161 0.978 0.076 0.327
0.898 0.923 0.773
0.322 0.533 0.947 0.690 0.702
Table 3 continues
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